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The Study of Bioactivity Behavior of Co-Cr-Mo/bio Active Glass Composite Fabricated by

Powder Metallurgy Method for Biomedical Applications










Cobalt based alloys and stainless steels were the first metallic materials that successfully used during the twentieth century in orthopedic applications. However Co based alloy is bioinert and may not present bioactivity in human body, which needed behavior for biomedical applications. This research will focused on the fabrication and bioactivity behavior of novel Co-Cr-Mo alloy (ASTM F-75) filled with different amounts of bioglass which will be prepared by powder metallurgy method. In this study, Co-Cr-Mo alloy (F-75) powder will be mixed with 2-10 wt. % of bioglass, before cold compacted at 550 MPa using a uniaxial press machine. The composites will be sintered at 1100°C for 2 h. Bioactivity behavior of sintered F-75/bioglass composites will be evaluated in vitro by immersing the composites into simulated body fluids (SBF) for up to 18 days. The test after immersion will be carried out in term of XRD, SEM, FTIR and pH analysis in order to observe the presence of the apatite layer on the surface of F-75/bioglass composites. The expected results will be the formation of apatite layer on the surface of the prepared F-75/bioglass composite. This apatite layer formation is considered as the mark of bioactivity, which formed on the composite surfaces will bind the materials of various kinds to living bone. Furthermore, the apatite formed is very similar to the bone mineral in its composition and structure. In summary, Co-Cr-Mo alloy, which is bioinert will be expected can be successfully converted into bioactive composite by adding bioglass particles.

Keywords: Biomaterials, Co-Cr alloy, bioglass